Methyl iodide → Methyl 2-(4-chloro-3-methoxyphenyl)propanoate

HRID 678041Notes

Reaction equation

HRID 678041 reaction equation
[CH2:29]1[O:30][CH2:31][CH2:32][CH2:33]1.[CH3:15][CH2:16][CH2:17][CH2:18][Li:19].[CH3:1][CH:2]([C:3](=[O:4])[O-:5])[c:6]1[cH:7][c:8]([O:13][CH3:14])[c:9]([Cl:12])[cH:10][cH:11]1.[CH3:27][I:28].[CH:20]([NH:21][CH:22]([CH3:23])[CH3:24])([CH3:25])[CH3:26]>>[CH3:1][CH:2]([C:3](=[O:4])[O:5][CH3:15])[c:6]1[cH:7][c:8]([O:13][CH3:14])[c:9]([Cl:12])[cH:10][cH:11]1

Participants

6

Reactant 5

HCID 6328Methyl iodideHCID 7912DiisopropylamineHCID 8028TetrahydrofuranHCID 178418339ButyllithiumHCID 178490571HCID 178490571, compound

Product 1

HCID 67266387Methyl 2-(4-chloro-3-methoxyphenyl)propanoate

Sources & evidence

ORD record
ord-22fe271c21234c50833d1ce8f163311c
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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