Chloride → Ethyl 2-(1-{[4-chloro-5-methyl-3-(trifluoromethyl)-1H-pyrazol-1-yl]acetyl}piperidin-4-yl)-1,3-thiazole-4-carboxylate

HRID 678154Notes

Reaction equation

HRID 678154 reaction equation
[CH2:2]([CH3:3])[O:4][C:5](=[O:6])[c:7]1[n:8][c:9]([CH:12]2[CH2:13][CH2:14][NH2+:15][CH2:16][CH2:17]2)[s:10][cH:11]1.[Cl-:1].[Cl:18][c:19]1[c:20]([C:29]([F:30])([F:31])[F:32])[n:21][n:22]([CH2:25][C:26](=[O:27])[OH:28])[c:23]1[CH3:24]>>[CH2:2]([CH3:3])[O:4][C:5](=[O:6])[c:7]1[n:8][c:9]([CH:12]2[CH2:13][CH2:14][N:15]([C:26]([CH2:25][n:22]3[n:21][c:20]([C:29]([F:30])([F:31])[F:32])[c:19]([Cl:18])[c:23]3[CH3:24])=[O:27])[CH2:16][CH2:17]2)[s:10][cH:11]1

Participants

4

Reactant 3

HCID 312ChlorideHCID 1876853(4-Chloro-5-methyl-3-trifluoromethyl-pyrazol-1-yl)-acetic acidHCID 178470097HCID 178470097, compound

Product 1

HCID 66911512Ethyl 2-(1-{[4-chloro-5-methyl-3-(trifluoromethyl)-1H-pyrazol-1-yl]acetyl}piperidin-4-yl)-1,3-thiazole-4-carboxylate

Sources & evidence

ORD record
ord-a3795e255ed940cf8af10efc3cf723cb
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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