Isopropanol → N'-(3-tert-Butoxycarbonylamino-2-hydroxy-4-phenyl-butyl)-N'-(4-pyridin-2-yl-benzyl)-hydrazinecarboxylic acid tert-butyl ester

HRID 678230Notes

Reaction equation

HRID 678230 reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[NH:8][NH:9][CH2:10][c:11]1[cH:12][cH:13][c:14](-[c:17]2[n:18][cH:19][cH:20][cH:21][cH:22]2)[cH:15][cH:16]1.[CH3:42][CH:43]([OH:44])[CH3:45].[O:23]1[CH2:24][CH:25]1[CH:26]([CH2:27][c:28]1[cH:29][cH:30][cH:31][cH:32][cH:33]1)[NH:34][C:35](=[O:36])[O:37][C:38]([CH3:39])([CH3:40])[CH3:41]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[NH:8][N:9]([CH2:10][c:11]1[cH:12][cH:13][c:14](-[c:17]2[n:18][cH:19][cH:20][cH:21][cH:22]2)[cH:15][cH:16]1)[CH2:24][CH:25]([OH:23])[CH:26]([CH2:27][c:28]1[cH:29][cH:30][cH:31][cH:32][cH:33]1)[NH:34][C:35](=[O:36])[O:37][C:38]([CH3:39])([CH3:40])[CH3:41]

Participants

4

Reactant 3

HCID 3776IsopropanolHCID 4571240tert-Butyl (1-(oxiran-2-yl)-2-phenylethyl)carbamateHCID 9796325tert-Butyl 2-{[4-(pyridin-2-yl)phenyl]methyl}hydrazine-1-carboxylate

Product 1

HCID 10940720N'-(3-tert-Butoxycarbonylamino-2-hydroxy-4-phenyl-butyl)-N'-(4-pyridin-2-yl-benzyl)-hydrazinecarboxylic acid tert-butyl ester

Sources & evidence

ORD record
ord-ddb42dd199f248618880740c8a70f647
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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