4-Toluenesulfonyl chloride → Ergosterol tosylate

HRID 67824Notes

Reaction equation

HRID 67824 reaction equation
[CH3:1][C@@H:2]([C@@H:10]1[C@@:14]2([CH3:29])[CH2:15][CH2:16][C@@H:17]3[C@@:22]4([CH3:28])[CH2:23][CH2:24][C@H:25]([OH:27])[CH2:26][C:21]4=[CH:20][CH:19]=[C:18]3[C@@H:13]2[CH2:12][CH2:11]1)/[CH:3]=[CH:4]/[C@@H:5]([CH:7]([CH3:9])[CH3:8])[CH3:6].[C:30]1([CH3:40])[CH:35]=[CH:34][C:33]([S:36](Cl)(=[O:38])=[O:37])=[CH:32][CH:31]=1>N1C=CC=CC=1>[CH3:1][C@@H:2]([C@@H:10]1[C@@:14]2([CH3:29])[CH2:15][CH2:16][C@@H:17]3[C@@:22]4([CH3:28])[CH2:23][CH2:24][C@H:25]([OH:27])[CH2:26][C:21]4=[CH:20][CH:19]=[C:18]3[C@@H:13]2[CH2:12][CH2:11]1)/[CH:3]=[CH:4]/[C@@H:5]([CH:7]([CH3:8])[CH3:9])[CH3:6].[S:36]([C:33]1[CH:34]=[CH:35][C:30]([CH3:40])=[CH:31][CH:32]=1)([O-:27])(=[O:38])=[O:37]

Participants

4

Reactant 2

HCID 73974-Toluenesulfonyl chlorideHCID 444679Ergosterol

Product 1

HCID 86738553Ergosterol tosylate

Reagents, catalysts & solvents 1

HCID 1049PyridineSolvent

Procedure

reacting ergosterol with p-toluenesulfonyl chloride in pyridine to obtain ergosterol tosylate;

Sources & evidence

ORD record
ord-fcdac4fb3d3a41439b1d32bdf7792ee1
Source dataset
uspto-grants-1982_08
Patent number
US04346226

Reaction notes

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