Dichloromethane → N-Pipecolyl-4-amino-5-benzyloxy-2-oxotetrahydrofuran

HRID 678355Notes

Reaction equation

HRID 678355 reaction equation
[C:1]([O:2][C:3](=[O:4])[N:8]1[CH:9]([C:10](=[O:11])[NH:12][CH:13]2[CH2:14][C:15](=[O:26])[O:16][CH:17]2[O:18][CH2:19][c:20]2[cH:21][cH:22][cH:23][cH:24][cH:25]2)[CH2:27][CH2:28][CH2:29][CH2:30]1)([CH3:5])([CH3:6])[CH3:7].[Cl:38][CH2:39][Cl:40].[OH:31][C:32]([C:33]([F:34])([F:35])[F:36])=[O:37]>>[NH:8]1[CH:9]([C:10](=[O:11])[NH:12][CH:13]2[CH2:14][C:15](=[O:26])[O:16][CH:17]2[O:18][CH2:19][c:20]2[cH:21][cH:22][cH:23][cH:24][cH:25]2)[CH2:27][CH2:28][CH2:29][CH2:30]1

Participants

4

Reactant 3

HCID 6344DichloromethaneHCID 6422Trifluoroacetic acidHCID 22977785HCID 22977785, compound

Product 1

HCID 66756117N-Pipecolyl-4-amino-5-benzyloxy-2-oxotetrahydrofuran

Sources & evidence

ORD record
ord-d391e67664f2489fbd5ba1db1de9fa41
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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