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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 678360Generated: October 25, 2026

1,2-Dichloroethane → 3-(2,4-Dichlorobenzylamino)-4-fluoropyrrolidine-1-carboxylic acid tert-butyl ester

https://huagongshe.com/reaction/678360

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1,2-DichloroethaneHCID 11—
ReactantAcetic AcidHCID 176—
ReactantSodium ionHCID 923—
ReactantHydroxideHCID 961—
Reactant2,4-DichlorobenzylamineHCID 1485—
ReactantTriacetoxyborohydrideHCID 2724942—
Reactant1-Boc-3-fluoro-4-pyrrolidinoneHCID 45158916—
Product3-(2,4-Dichlorobenzylamino)-4-fluoropyrrolidine-1-carboxylic acid tert-butyl esterHCID 66855281—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (3/10)
ORD IDord-83ad048b557448998c64eacc1b49e401
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (3/10)