1,2-Dichloroethane → 3-(2,4-Dichlorobenzylamino)-4-fluoropyrrolidine-1-carboxylic acid tert-butyl ester
Reaction equation
[C:15]([CH3:16])([CH3:17])([CH3:18])[O:19][C:20](=[O:21])[N:22]1[CH2:23][CH:24]([F:28])[C:25](=[O:27])[CH2:26]1.[C:1]([O:2][BH-:3]([O:4][C:5](=[O:6])[CH3:7])[O:8][C:9](=[O:10])[CH3:11])(=[O:12])[CH3:13].[CH3:45][C:46](=[O:47])[OH:48].[Cl:29][c:30]1[c:31]([CH2:32][NH2:33])[cH:34][cH:35][c:36]([Cl:38])[cH:37]1.[Cl:41][CH2:42][CH2:43][Cl:44].[Na+:14].[Na+:40].[OH-:39]>>[C:15]([CH3:16])([CH3:17])([CH3:18])[O:19][C:20](=[O:21])[N:22]1[CH2:23][CH:24]([F:28])[CH:25]([NH:33][CH2:32][c:31]2[c:30]([Cl:29])[cH:37][c:36]([Cl:38])[cH:35][cH:34]2)[CH2:26]1Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-83ad048b557448998c64eacc1b49e401
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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