Methane → Tert-butyl 4-[4-chloro-1-hydrazinocarbonyl-butan-1-yl]piperidine-1-carboxylate

HRID 678475Notes

Reaction equation

HRID 678475 reaction equation
[C:35].[CH2:1]([O:2][C:3](=[O:4])[NH:11][NH:12][C:13](=[O:14])[CH:15]([CH2:16][CH2:17][CH2:18][Cl:19])[CH:20]1[CH2:21][CH2:22][N:23]([C:26](=[O:27])[O:28][C:29]([CH3:30])([CH3:31])[CH3:32])[CH2:24][CH2:25]1)[c:5]1[cH:6][cH:7][cH:8][cH:9][cH:10]1.[CH3:33][OH:34].[Pd:36]>>[NH2:11][NH:12][C:13](=[O:14])[CH:15]([CH2:16][CH2:17][CH2:18][Cl:19])[CH:20]1[CH2:21][CH2:22][N:23]([C:26](=[O:27])[O:28][C:29]([CH3:30])([CH3:31])[CH3:32])[CH2:24][CH2:25]1

Participants

5

Reactant 4

HCID 297MethaneHCID 887MethanolHCID 23938PalladiumHCID 66839389tert-butyl 4-[1-(N'-benzyloxycarbonyl-hydrazinocarbonyl)-4-chlorobutan-1-yl]piperidine-1-carboxylate

Product 1

HCID 66839238Tert-butyl 4-[4-chloro-1-hydrazinocarbonyl-butan-1-yl]piperidine-1-carboxylate

Sources & evidence

ORD record
ord-473769fcc63c4385b48130c2dfc6f920
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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