Hydrochloric Acid → [6-Fluoro-4-(piperidin-4-yloxy)-naphthalen-2-yl]-acetic acid methyl ester

HRID 678731Notes

Reaction equation

HRID 678731 reaction equation
[C:1]([O:2][C:3](=[O:4])[N:8]1[CH2:9][CH2:10][CH:11]([O:14][c:15]2[cH:16][c:17]([CH2:26][C:27](=[O:28])[O:29][CH3:30])[cH:18][c:19]3[cH:20][cH:21][c:22]([F:25])[cH:23][c:24]23)[CH2:12][CH2:13]1)([CH3:5])([CH3:6])[CH3:7].[CH3:32][OH:33].[ClH:31]>>[NH:8]1[CH2:9][CH2:10][CH:11]([O:14][c:15]2[cH:16][c:17]([CH2:26][C:27](=[O:28])[O:29][CH3:30])[cH:18][c:19]3[cH:20][cH:21][c:22]([F:25])[cH:23][c:24]23)[CH2:12][CH2:13]1

Participants

4

Reactant 3

HCID 313Hydrochloric AcidHCID 887MethanolHCID 593267504-(7-Fluoro-3-methoxycarbonylmethyl-naphthalen-1-yloxy)-piperidine-1-carboxylic acid tert-butyl ester

Product 1

HCID 59326737[6-Fluoro-4-(piperidin-4-yloxy)-naphthalen-2-yl]-acetic acid methyl ester

Sources & evidence

ORD record
ord-94ea90a3ba204ddcbb69be3708c7ad50
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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