Trifluoroacetic acid → N-{1-[4-(2-Ethyl-thiazol-5-yl)-4-hydroxy-cyclohexyl]-azetidin-3-yl}-2-[1-(2,2,2-trifluoro-ethyl)-5-trifluoromethyl-1H-indazol-3-ylamino]-acetamide
Reaction equation
[CH2:35]([CH3:36])[c:37]1[s:38][c:39]([C:42]2([OH:49])[CH2:43][CH2:44][C:45](=[O:48])[CH2:46][CH2:47]2)[cH:40][n:41]1.[F:28][C:29]([F:30])([F:31])[C:32]([OH:33])=[O:34].[NH:1]1[CH2:2][CH:3]([NH:5][C:6]([CH2:7][NH:8][c:9]2[n:10][n:11]([CH2:22][C:23]([F:24])([F:25])[F:26])[c:12]3[cH:13][cH:14][c:15]([C:18]([F:19])([F:20])[F:21])[cH:16][c:17]23)=[O:27])[CH2:4]1>>[N:1]1([CH:45]2[CH2:44][CH2:43][C:42]([c:39]3[s:38][c:37]([CH2:35][CH3:36])[n:41][cH:40]3)([OH:49])[CH2:47][CH2:46]2)[CH2:2][CH:3]([NH:5][C:6]([CH2:7][NH:8][c:9]2[n:10][n:11]([CH2:22][C:23]([F:24])([F:25])[F:26])[c:12]3[cH:13][cH:14][c:15]([C:18]([F:19])([F:20])[F:21])[cH:16][c:17]23)=[O:27])[CH2:4]1Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-3577e9f0c4724721bf0e5f1c61e06700
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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