Hydrochloric Acid → 2-Acetylthio-3-methoxybenzoic acid

HRID 67900Notes

Reaction equation

HRID 67900 reaction equation
[SH:1][C:2]1[C:10]([O:11][CH3:12])=[CH:9][CH:8]=[CH:7][C:3]=1[C:4]([OH:6])=[O:5].[C:13](OC(=O)C)(=[O:15])[CH3:14].Cl>C(O)(=O)C>[C:13]([S:1][C:2]1[C:10]([O:11][CH3:12])=[CH:9][CH:8]=[CH:7][C:3]=1[C:4]([OH:6])=[O:5])(=[O:15])[CH3:14]

Participants

5

Reactant 3

HCID 313Hydrochloric AcidHCID 7918Acetic AnhydrideHCID 166556102-Mercapto-3-methoxybenzoic acid

Product 1

HCID 204652112-Acetylthio-3-methoxybenzoic acid

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent

Procedure

A solution of 2-mercapto-3-methoxybenzoic acid (14.6 g, 79 mmol), acetic anhydride (9.7 g, 95 mmol) and glacial acetic acid (35 ml) was refluxed 15 minutes, then cooled and poured into dilute hydrochloric acid.

Workup

  1. temperaturecooled

Sources & evidence

ORD record
ord-bca570220ba24229a752eb77e5c21fd5
Source dataset
uspto-grants-1982_08
Patent number
US04347246

Reaction notes

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