Dimethylformamide → 5-Chlorocarbonylphthalide

HRID 679274Notes

Reaction equation

HRID 679274 reaction equation
[C:5](=[O:6])([OH:7])[c:8]1[cH:9][c:10]2[c:15]([cH:16][cH:17]1)[C:13](=[O:14])[O:12][CH2:11]2.[CH3:18][N:19]([CH3:20])[CH:21]=[O:22].[S:1]([Cl:2])([Cl:3])=[O:4]>>[Cl:3][C:5](=[O:6])[c:8]1[cH:9][c:10]2[c:15]([cH:16][cH:17]1)[C:13](=[O:14])[O:12][CH2:11]2

Participants

4

Reactant 3

HCID 6228DimethylformamideHCID 24386Thionyl ChlorideHCID 785171,3-Dihydro-1-oxoisobenzofuran-5-carboxylic acid

Product 1

HCID 98155555-Chlorocarbonylphthalide

Sources & evidence

ORD record
ord-e346b8b3e00b42a0a6e31a84c6160fc2
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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