HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → 1-[3-(3,5-Bistrifluoromethylphenyl)-2-propynyl]piperidine hydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | HCID 2804025 | HCID 2804025 | — |
| Solvent | Diethyl Ether | HCID 3283 | — |
| Product | 1-[3-(3,5-Bistrifluoromethylphenyl)-2-propynyl]piperidine hydrochloride | HCID 2804024 | — |
Reaction Steps
An excess of dry HCl gas was passed through a solution of 1-(3,5-bistrifluoromethylphenyl)-3-piperidinoprop-1-yne (2.26 g) in dry diethyl ether (200 ml). Filtration, washing (diethyl ether) and drying of the resulting white precipitate gave 2.16 g of a fine white powder of melting point 214.5° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07084158B2 |
| Source dataset | uspto-grants-2006_08 |
| ORD ID | ord-ed06c24c01b04411accf6dff0f2cccde |
| Source note | uspto-grants-2006_08 |