Hydrogen Bromide → 4'-(2-Amino-4-thiazolyl)-6-methyl-N-[3-(4-morpholinyl)phenyl][1,1'-biphenyl]-3-carboxamide

HRID 679413Notes

Reaction equation

HRID 679413 reaction equation
[Br:2][c:3]1[cH:4][cH:5][c:6](-[c:9]2[n:10][c:11]([NH2:14])[s:12][cH:13]2)[cH:7][cH:8]1.[BrH:1].[CH3:15][c:16]1[c:17]([B:37]2[O:38][C:39]([CH3:40])([CH3:41])[C:42]([CH3:43])([CH3:44])[O:45]2)[cH:18][c:19]([C:20](=[O:21])[NH:22][c:23]2[cH:24][c:25]([N:29]3[CH2:30][CH2:31][O:32][CH2:33][CH2:34]3)[cH:26][cH:27][cH:28]2)[cH:35][cH:36]1>>[c:3]1(-[c:17]2[c:16]([CH3:15])[cH:36][cH:35][c:19]([C:20](=[O:21])[NH:22][c:23]3[cH:24][c:25]([N:29]4[CH2:30][CH2:31][O:32][CH2:33][CH2:34]4)[cH:26][cH:27][cH:28]3)[cH:18]2)[cH:4][cH:5][c:6](-[c:9]2[n:10][c:11]([NH2:14])[s:12][cH:13]2)[cH:7][cH:8]1

Participants

4

Reactant 3

HCID 260Hydrogen BromideHCID 6206834-(4-Bromophenyl)-1,3-thiazol-2-amineHCID 597915214-methyl-N-[3-(4-morpholinyl)phenyl]-3-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)benzamide

Product 1

HCID 99563634'-(2-Amino-4-thiazolyl)-6-methyl-N-[3-(4-morpholinyl)phenyl][1,1'-biphenyl]-3-carboxamide

Sources & evidence

ORD record
ord-140d8ef8f1a74132a3c9fdf5b2f5883a
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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