Triphenylphosphine → 4-(2,4-Dichloro-5-methoxyphenylamino)-7-(5-(morpholinomethyl)pyridin-2-yl)quinoline-3-carbonitrile
Reaction equation
[CH2:25]([Sn:26]([CH2:27][CH2:28][CH2:29][CH3:43])([c:30]1[cH:31][cH:32][c:33]([CH2:36][N:37]2[CH2:38][CH2:39][O:40][CH2:41][CH2:42]2)[cH:34][n:35]1)[CH2:44][CH2:45][CH2:46][CH3:47])[CH2:48][CH2:49][CH3:50].[CH2:51]1[O:52][CH2:53][CH2:54][O:55][CH2:56]1.[Cl:1][c:2]1[c:3]([NH:4][c:5]2[c:6]([C:16]#[N:17])[cH:7][n:8][c:9]3[cH:10][c:11]([I:15])[cH:12][cH:13][c:14]23)[cH:18][c:19]([O:23][CH3:24])[c:20]([Cl:22])[cH:21]1.[Pd:57]([Cl:58])[Cl:59].[c:60]1([P:61]([c:62]2[cH:63][cH:64][cH:65][cH:66][cH:67]2)[c:68]2[cH:69][cH:70][cH:71][cH:72][cH:73]2)[cH:74][cH:75][cH:76][cH:77][cH:78]1.[c:79]1([P:80]([c:81]2[cH:82][cH:83][cH:84][cH:85][cH:86]2)[c:87]2[cH:88][cH:89][cH:90][cH:91][cH:92]2)[cH:93][cH:94][cH:95][cH:96][cH:97]1>>[Cl:1][c:2]1[c:3]([NH:4][c:5]2[c:6]([C:16]#[N:17])[cH:7][n:8][c:9]3[cH:10][c:11](-[c:30]4[cH:31][cH:32][c:33]([CH2:36][N:37]5[CH2:38][CH2:39][O:40][CH2:41][CH2:42]5)[cH:34][n:35]4)[cH:12][cH:13][c:14]23)[cH:18][c:19]([O:23][CH3:24])[c:20]([Cl:22])[cH:21]1Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-240aa64042154accaf85dfe3511a32ff
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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