Tetrahydrofuran → 2-[5-(3-Ethynyl-5-{[4-(trifluoromethyl)pyrimidin-2-yl]amino}phenyl)-1,3-thiazol-2-yl]propan-2-ol
Reaction equation
[CH2:34]([N+:35]([CH2:36][CH2:37][CH2:38][CH3:39])([CH2:40][CH2:41][CH2:42][CH3:43])[CH2:44][CH2:45][CH2:46][CH3:47])[CH2:48][CH2:49][CH3:50].[CH2:51]1[O:52][CH2:53][CH2:54][CH2:55]1.[F-:33].[F:1][C:2]([c:3]1[n:4][c:5]([NH:9][c:10]2[cH:11][c:12](-[c:22]3[cH:23][n:24][c:25]([C:27]([CH3:28])([CH3:29])[OH:30])[s:26]3)[cH:13][c:14]([C:16]#[C:17][Si:18]([CH3:19])([CH3:20])[CH3:21])[cH:15]2)[n:6][cH:7][cH:8]1)([F:31])[F:32]>>[F:1][C:2]([c:3]1[n:4][c:5]([NH:9][c:10]2[cH:11][c:12](-[c:22]3[cH:23][n:24][c:25]([C:27]([CH3:28])([CH3:29])[OH:30])[s:26]3)[cH:13][c:14]([C:16]#[CH:17])[cH:15]2)[n:6][cH:7][cH:8]1)([F:31])[F:32]Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-6529e95ee2834541b8f9484d792e8a3d
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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