Dichloromethane → 6-fluoro-5-(7H-pyrrolo[2,3-d]pyrimidin-5-ylmethyl)-pyridin-2-ylamine
Reaction equation
[Cl:35][CH2:36][Cl:37].[F:1][c:2]1[c:3]([CH2:18][c:19]2[cH:20][nH:21][c:22]3[n:23][cH:24][n:25][cH:26][c:27]23)[cH:4][cH:5][c:6]([NH:8][CH2:9][c:10]2[cH:11][cH:12][c:13]([O:14][CH3:15])[cH:16][cH:17]2)[n:7]1.[OH:28][C:29]([C:30]([F:31])([F:32])[F:33])=[O:34]>>[F:1][c:2]1[c:3]([CH2:18][c:19]2[cH:20][nH:21][c:22]3[n:23][cH:24][n:25][cH:26][c:27]23)[cH:4][cH:5][c:6]([NH2:8])[n:7]1Participants
4
Sources & evidence
- ORD record
- ord-747c6f7e23ef43a79817b48aebee924a
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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