Acetate → 2-Chloro-3-(2-methoxypyridin-4-yl)pyridine

HRID 679906Notes

Reaction equation

HRID 679906 reaction equation
[C:20](=[O:21])([O-:22])[O-:23].[CH3:32][CH2:33][O:34][C:35]([CH3:36])=[O:37].[Cl:10][c:11]1[n:12][cH:13][cH:14][cH:15][c:16]1[B:17]([OH:18])[OH:19].[I:1][c:2]1[cH:3][c:4]([O:8][CH3:9])[n:5][cH:6][cH:7]1.[Na+:24].[Na+:25].[O-:39][C:40]([CH3:41])=[O:42].[O-:43][C:44]([CH3:45])=[O:46].[O:26]1[CH2:27][CH2:28][O:29][CH2:30][CH2:31]1.[OH2:47].[Pd+2:38]>>[c:2]1(-[c:16]2[c:11]([Cl:10])[n:12][cH:13][cH:14][cH:15]2)[cH:3][c:4]([O:8][CH3:9])[n:5][cH:6][cH:7]1

Participants

10

Reactant 9

HCID 175Acetate2×HCID 923Sodium ion2×HCID 962WaterHCID 8857Ethyl AcetateHCID 19660Carbonate IonHCID 312751,4-DioxaneHCID 105144Allyl(1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene)chloropalladium(II)HCID 2762704(2-Chloropyridin-3-yl)boronic acidHCID 150197954-Iodo-2-methoxypyridine

Product 1

HCID 583966532-Chloro-3-(2-methoxypyridin-4-yl)pyridine

Sources & evidence

ORD record
ord-a536a151918f4634aef0fc456b495092
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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