HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → Hydrochloric Acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Methanol | HCID 887 | — |
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | alpha-Vinyltryptophan methyl ester | HCID 54086905 | — |
| Solvent | Water | HCID 962 | — |
| Product | Hydrochloric Acid | HCID 313 | — |
| Product | HCID 70529730 | HCID 70529730 | — |
Reaction Steps
Treatment of α-vinyltryptophan methyl ester in 1.1 methanol:water with two equivalents of sodium hydroxide, neutralization of the reaction mixture with 1 N aqueous hydrochloric acid, and purification of the crude amino acid on DOWEX 50W-X4 cation exchange resin (elution with water and then 2 N aqueous hydrochloric acid) gives α-vinyltryptophan hydrochloride.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04347375 |
| Source dataset | uspto-grants-1982_08 |
| ORD ID | ord-f52cc0bab89e4b419ae002d32d939afd |
| Source note | uspto-grants-1982_08 |