Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 680102Generated: October 26, 2026

Diethyl Ether → 5-Chloro-3-((trimethylsilyl)ethynyl)pyridin-2-amine

https://huagongshe.com/reaction/680102

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDiethyl EtherHCID 3283—
ReactantTetrahydrofuranHCID 8028—
ReactantTriethylamineHCID 8471—
ReactantTriphenylphosphineHCID 11776—
ReactantPalladium ChlorideHCID 24290—
ReactantTrimethylsilylacetyleneHCID 66111—
ReactantCopper iodideHCID 83717—
Reactant2-Amino-5-chloro-3-iodopyridineHCID 11076010—
Product5-Chloro-3-((trimethylsilyl)ethynyl)pyridin-2-amineHCID 24729465—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (3/10)
ORD IDord-fc240b9a4d064f91b23fb9ee32c630f5
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (3/10)