HRID680102

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID3283

Diethyl Ether

C4H10O

HCID8028

Tetrahydrofuran

C4H8O

HCID8471

Triethylamine

C6H15N

HCID11776

Triphenylphosphine

C18H15P

2 次

HCID24290

未命名化合物

HCID66111

Trimethylsilylacetylene

C5H10Si

HCID83717

Copper iodide (CuI2)

CuI2

HCID11076010

2-AMINO-5-CHLORO-3-IODOPYRIDINE

C5H4ClIN2

PRODUCTS

生成物

HCID24729465

5-Chloro-3-[(trimethylsilyl)ethynyl]pyridin-2-amine

C10H13ClN2Si

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-fc240b9a4d064f91b23fb9ee32c630f5
来源数据集: Training data from https://doi.org/10.1039/C8SC04228D (3/10)
DOI: 10.1039/C8SC04228D
来源说明: Training data from https://doi.org/10.1039/C8SC04228D (3/10)

反应 SMILES

[CH2:10]1[O:11][CH2:12][CH2:13][CH2:14]1.[CH3:15][CH2:16][N:17]([CH2:18][CH3:19])[CH2:20][CH3:21].[CH3:22][Si:23]([CH3:24])([CH3:25])[C:26]#[CH:27].[CH3:72][CH2:73][O:74][CH2:75][CH3:76].[Cl:1][c:2]1[cH:3][c:4]([I:9])[c:5]([NH2:8])[n:6][cH:7]1.[Cu:28]([I:29])[I:30].[Pd:31]([Cl:32])[Cl:33].[c:34]1([P:35]([c:36]2[cH:37][cH:38][cH:39][cH:40][cH:41]2)[c:42]2[cH:43][cH:44][cH:45][cH:46][cH:47]2)[cH:48][cH:49][cH:50][cH:51][cH:52]1.[c:53]1([P:54]([c:55]2[cH:56][cH:57][cH:58][cH:59][cH:60]2)[c:61]2[cH:62][cH:63][cH:64][cH:65][cH:66]2)[cH:67][cH:68][cH:69][cH:70][cH:71]1>>[Cl:1][c:2]1[cH:3][c:4]([C:27]#[C:26][Si:23]([CH3:22])([CH3:24])[CH3:25])[c:5]([NH2:8])[n:6][cH:7]1