Hydrochloric Acid → 4-[1-Azetidin-3-yl-4-(4-fluorophenyl)-1H-imidazol-5-yl]pyrimidin-2-amine

HRID 680252Notes

Reaction equation

HRID 680252 reaction equation
[CH3:32][OH:33].[ClH:31].[NH2:1][c:2]1[n:3][cH:4][cH:5][c:6](-[c:8]2[c:9](-[c:24]3[cH:25][cH:26][c:27]([F:30])[cH:28][cH:29]3)[n:10][cH:11][n:12]2[CH:13]2[CH2:14][N:15]([C:17]([O:18][C:19]([CH3:20])([CH3:21])[CH3:22])=[O:23])[CH2:16]2)[n:7]1>>[NH2:1][c:2]1[n:3][cH:4][cH:5][c:6](-[c:8]2[c:9](-[c:24]3[cH:25][cH:26][c:27]([F:30])[cH:28][cH:29]3)[n:10][cH:11][n:12]2[CH:13]2[CH2:14][NH:15][CH2:16]2)[n:7]1

Participants

4

Reactant 3

HCID 313Hydrochloric AcidHCID 887MethanolHCID 57461719HCID 57461719, compound

Product 1

HCID 574617124-[1-Azetidin-3-yl-4-(4-fluorophenyl)-1H-imidazol-5-yl]pyrimidin-2-amine

Sources & evidence

ORD record
ord-64df958f04f049f98c27c2a71f02a99b
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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