Tetrahydrofuran → 1-(2-Fluorophenyl)-3-(2-(quinolin-4-ylmethyl)-1,2,3,4-tetrahydroisoquinolin-5-yl)urea
Reaction equation
[F:23][c:24]1[c:25]([N:30]=[C:31]=[O:32])[cH:26][cH:27][cH:28][cH:29]1.[O:33]1[CH2:34][CH2:35][CH2:36][CH2:37]1.[n:1]1[cH:2][cH:3][c:4]([CH2:11][N:12]2[CH2:13][c:14]3[cH:15][cH:16][cH:17][c:18]([NH2:22])[c:19]3[CH2:20][CH2:21]2)[c:5]2[cH:6][cH:7][cH:8][cH:9][c:10]12>>[n:1]1[cH:2][cH:3][c:4]([CH2:11][N:12]2[CH2:13][c:14]3[cH:15][cH:16][cH:17][c:18]([NH:22][C:31]([NH:30][c:25]4[c:24]([F:23])[cH:29][cH:28][cH:27][cH:26]4)=[O:32])[c:19]3[CH2:20][CH2:21]2)[c:5]2[cH:6][cH:7][cH:8][cH:9][c:10]12Participants
4
Sources & evidence
- ORD record
- ord-802548f59ff043a8a47fe9e55597ac63
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
Loading…