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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 680716Generated: October 27, 2026

1-(4-Bromophenyl)-2,2-difluoroethan-1-ol → 2-(4-(2,2-Difluoro-1-hydroxyethyl)phenyl)-8-(isobutylsulfonyl)-2,8-diazaspiro[4.5]decan-1-one

https://huagongshe.com/reaction/680716

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(4-Bromophenyl)-2,2-difluoroethan-1-olHCID 15942204—
Reactant8-(Isobutylsulfonyl)-2,8-diazaspiro[4.5]decan-1-oneHCID 59577951—
Reactant8-(Isobutylsulfonyl)-2-(4-(2,2,2-trifluoro-1-hydroxyethyl)phenyl)-2,8-diazaspiro[4.5]decan-1-oneHCID 59578029—
Product2-(4-(2,2-Difluoro-1-hydroxyethyl)phenyl)-8-(isobutylsulfonyl)-2,8-diazaspiro[4.5]decan-1-oneHCID 59578095—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (3/10)
ORD IDord-c9c603f9d0424b61ae195d5a90b410a3
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (3/10)