1-Butanol → 8-Ethyl-N-[3-(trifluoromethyl)phenyl]-8H-pyrazolo[4',3':5,6]pyrido[3,4-e][1,2,4]triazolo[1,5-a]pyrimidin-5-amine

HRID 681024Notes

Reaction equation

HRID 681024 reaction equation
[CH2:38]([OH:39])[CH2:40][CH2:41][CH3:42].[CH3:20][CH2:21][N:22]([CH2:23][CH3:24])[CH2:25][CH3:26].[Cl:1][c:2]1[n:3][c:4]2[n:5]([c:6]3[c:7]1[cH:8][n:9][c:10]1[c:11]3[cH:12][n:13][n:14]1[CH2:15][CH3:16])[n:17][cH:18][n:19]2.[F:27][C:28]([c:29]1[cH:30][c:31]([NH2:32])[cH:33][cH:34][cH:35]1)([F:36])[F:37]>>[c:2]1([NH:32][c:31]2[cH:30][c:29]([C:28]([F:27])([F:36])[F:37])[cH:35][cH:34][cH:33]2)[n:3][c:4]2[n:5]([c:6]3[c:7]1[cH:8][n:9][c:10]1[c:11]3[cH:12][n:13][n:14]1[CH2:15][CH3:16])[n:17][cH:18][n:19]2

Participants

5

Reactant 4

HCID 2631-ButanolHCID 73753-(Trifluoromethyl)anilineHCID 8471TriethylamineHCID 227584865-Chloro-8-ethyl-8H-pyrazolo[4',3':5,6]pyrido[3,4-e][1,2,4]-triazolo[1,5-a]pyrimidine

Product 1

HCID 227585048-Ethyl-N-[3-(trifluoromethyl)phenyl]-8H-pyrazolo[4',3':5,6]pyrido[3,4-e][1,2,4]triazolo[1,5-a]pyrimidin-5-amine

Sources & evidence

ORD record
ord-25a5079ce1d04978a7214e93b76e03ce
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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