Phosphorus oxychloride → 2-Chloro-3-(4-fluorophenyl)pyrido[3,2-d]pyrimidin-4(3H)-one

HRID 681080Notes

Reaction equation

HRID 681080 reaction equation
[F:1][c:2]1[cH:3][cH:4][c:5](-[n:8]2[c:9](=[S:19])[nH:10][c:11]3[c:12]([c:13]2=[O:14])[n:15][cH:16][cH:17][cH:18]3)[cH:6][cH:7]1.[P:20]([Cl:21])([Cl:22])([Cl:23])=[O:24]>>[F:1][c:2]1[cH:3][cH:4][c:5](-[n:8]2[c:9]([Cl:22])[n:10][c:11]3[c:12]([c:13]2=[O:14])[n:15][cH:16][cH:17][cH:18]3)[cH:6][cH:7]1

Participants

3

Reactant 2

HCID 24813Phosphorus oxychlorideHCID 576141483-(4-Fluorophenyl)-2-thioxo-2,3-dihydropyrido[3,2-d]pyrimidin-4(1H)-one

Product 1

HCID 576141462-Chloro-3-(4-fluorophenyl)pyrido[3,2-d]pyrimidin-4(3H)-one

Sources & evidence

ORD record
ord-2d5e3277296c4774bec74712799cc3b6
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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