Dimethyl Sulfoxide → (E)-N-((1-(4-(2-(acetylimino)pyridin-1(2H)-yl)phenyl)-1H-imidazol-4-yl)methyl)-5-chlorothiophene-2-carboxamide

HRID 681099Notes

Reaction equation

HRID 681099 reaction equation
[CH3:50][S:51]([CH3:52])=[O:53].[Cl:18][c:19]1[cH:20][cH:21][c:22]([C:24](=[O:25])[NH:26][CH2:27][c:28]2[n:29][cH:30][nH:31][cH:32]2)[s:23]1.[Cu:54][I:55].[I:1][c:2]1[cH:3][cH:4][c:5](-[n:8]2[c:9](=[N:14][C:15]([CH3:16])=[O:17])[cH:10][cH:11][cH:12][cH:13]2)[cH:6][cH:7]1.[K+:44].[K+:45].[O-:46][C:47]([O-:48])=[O:49].[OH:33][c:34]1[cH:35][cH:36][cH:37][c:38]2[c:39]1[n:40][cH:41][cH:42][cH:43]2>>[c:2]1(-[n:31]2[cH:30][n:29][c:28]([CH2:27][NH:26][C:24]([c:22]3[cH:21][cH:20][c:19]([Cl:18])[s:23]3)=[O:25])[cH:32]2)[cH:3][cH:4][c:5](-[n:8]2[c:9](=[N:14][C:15]([CH3:16])=[O:17])[cH:10][cH:11][cH:12][cH:13]2)[cH:6][cH:7]1

Participants

8

Reactant 7

HCID 679Dimethyl SulfoxideHCID 813Potassium Cation2×HCID 19238-HydroxyquinolineHCID 19660Carbonate IonHCID 24350Copper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI)HCID 66974112HCID 66974112, compoundHCID 178523075HCID 178523075, compound

Product 1

HCID 24760378(E)-N-((1-(4-(2-(acetylimino)pyridin-1(2H)-yl)phenyl)-1H-imidazol-4-yl)methyl)-5-chlorothiophene-2-carboxamide

Sources & evidence

ORD record
ord-b4cf00cf180640d694f64de23c98de29
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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