Trifluoroacetic acid → [3-[2-Chloro-4-[(3,3-dimethyl-1-oxa-6-azaspiro[3.3]heptan-6-yl)methyl]phenoxy]azetidin-1-yl]-(5-phenyl-1,3,4-oxadiazol-2-yl)methanone

HRID 681214Notes

Reaction equation

HRID 681214 reaction equation
[CH3:8][C:9]1([CH3:16])[CH2:10][O:11][C:12]12[CH2:13][NH:14][CH2:15]2.[Cl:17][c:18]1[cH:19][c:20]([CH:21]=[O:22])[cH:23][cH:24][c:25]1[O:26][CH:27]1[CH2:28][N:29]([C:31](=[O:32])[c:33]2[o:34][c:35](-[c:38]3[cH:39][cH:40][cH:41][cH:42][cH:43]3)[n:36][n:37]2)[CH2:30]1.[F:1][C:2]([F:3])([F:4])[C:5]([OH:6])=[O:7]>>[CH3:8][C:9]1([CH3:16])[CH2:10][O:11][C:12]12[CH2:13][N:14]([CH2:21][c:20]1[cH:19][c:18]([Cl:17])[c:25]([O:26][CH:27]3[CH2:28][N:29]([C:31](=[O:32])[c:33]4[o:34][c:35](-[c:38]5[cH:39][cH:40][cH:41][cH:42][cH:43]5)[n:36][n:37]4)[CH2:30]3)[cH:24][cH:23]1)[CH2:15]2

Participants

4

Reactant 3

HCID 6422Trifluoroacetic acidHCID 580431283-Chloro-4-(1-(5-phenyl-1,3,4-oxadiazole-2-carbonyl)azetidin-3-yloxy)benzaldehydeHCID 594208533,3-Dimethyl-1-oxa-6-azaspiro[3.3]heptane

Product 1

HCID 49802135[3-[2-Chloro-4-[(3,3-dimethyl-1-oxa-6-azaspiro[3.3]heptan-6-yl)methyl]phenoxy]azetidin-1-yl]-(5-phenyl-1,3,4-oxadiazol-2-yl)methanone

Sources & evidence

ORD record
ord-98002f0d8a4e48519bb8b57011aff90f
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

Loading…