Acetate → 4-[5-(3,4,5-Trimethoxy-phenyl)-2,5-dihydrofuran-2-yl]-benzoic Acid Ethyl Ester

HRID 681228Notes

Reaction equation

HRID 681228 reaction equation
[CH2:18]([CH3:19])[O:20][C:21]([c:22]1[cH:23][cH:24][c:25]([I:28])[cH:26][cH:27]1)=[O:29].[CH3:1][O:2][c:3]1[cH:4][c:5]([CH:13]2[O:14][CH:15]=[CH:16][CH2:17]2)[cH:6][c:7]([O:11][CH3:12])[c:8]1[O:9][CH3:10].[CH3:49][C:50]#[N:51].[O-:53][C:54]([CH3:55])=[O:56].[O-:57][C:58]([CH3:59])=[O:60].[Pd+2:52].[c:30]1([P:31]([c:32]2[cH:33][cH:34][cH:35][cH:36][cH:37]2)[c:38]2[cH:39][cH:40][cH:41][cH:42][cH:43]2)[cH:44][cH:45][cH:46][cH:47][cH:48]1>>[CH3:1][O:2][c:3]1[cH:4][c:5]([CH:13]2[O:14][CH:15]([c:25]3[cH:24][cH:23][c:22]([C:21]([O:20][CH2:18][CH3:19])=[O:29])[cH:27][cH:26]3)[CH:16]=[CH:17]2)[cH:6][c:7]([O:11][CH3:12])[c:8]1[O:9][CH3:10]

Participants

7

Reactant 6

HCID 175Acetate2×HCID 6342AcetonitrileHCID 11776TriphenylphosphineHCID 105144Allyl(1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene)chloropalladium(II)HCID 142891Ethyl 4-iodobenzoateHCID 224789522-(3,4,5-Trimethoxyphenyl)-2,3-dihydrofuran

Product 1

HCID 207859344-[5-(3,4,5-Trimethoxy-phenyl)-2,5-dihydrofuran-2-yl]-benzoic Acid Ethyl Ester

Sources & evidence

ORD record
ord-4d06cc70cf3b4c5daada7dc1100af94e
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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