3-Pyridinemethanamine → 4-Chloro-6-(2-hydroxy-ethylamino)-2-[(pyridin-3-ylmethyl)-amino]-pyrimidine-5-carbonitrile
Reaction equation
[CH2:26]([N:27]([CH:28]([CH3:29])[CH3:30])[CH:31]([CH3:32])[CH3:33])[CH3:34].[Cl:1][c:2]1[n:3][c:4]([S:14]([CH3:15])(=[O:16])=[O:17])[n:5][c:6]([NH:10][CH2:11][CH2:12][OH:13])[c:7]1[C:8]#[N:9].[O:35]1[CH2:36][CH2:37][O:38][CH2:39][CH2:40]1.[cH:18]1[c:19]([CH2:24][NH2:25])[cH:20][cH:21][cH:22][n:23]1>>[Cl:1][c:2]1[n:3][c:4]([NH:25][CH2:24][c:19]2[cH:18][n:23][cH:22][cH:21][cH:20]2)[n:5][c:6]([NH:10][CH2:11][CH2:12][OH:13])[c:7]1[C:8]#[N:9]Participants
5
Sources & evidence
- ORD record
- ord-6ce7cbfcfea345468f285fd435ede98d
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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