Hydrochloric Acid → Ethyl 4-[(3-bromophenyl)amino]-5,6,7,8-tetrahydro[1]benzothieno[2,3-d]pyrimidine-7-carboxylate

HRID 681356Notes

Reaction equation

HRID 681356 reaction equation
[Br:20][c:21]1[cH:22][c:23]([NH2:24])[cH:25][cH:26][cH:27]1.[CH2:1]([CH3:2])[O:3][C:4](=[O:5])[CH:6]1[CH2:7][c:8]2[c:9]([c:10]3[c:11]([n:12][cH:13][n:14][c:15]3[Cl:16])[s:17]2)[CH2:18][CH2:19]1.[CH3:29][CH2:30][OH:31].[ClH:28]>>[CH2:1]([CH3:2])[O:3][C:4](=[O:5])[CH:6]1[CH2:7][c:8]2[c:9]([c:10]3[c:11]([n:12][cH:13][n:14][c:15]3[NH:24][c:23]3[cH:22][c:21]([Br:20])[cH:27][cH:26][cH:25]3)[s:17]2)[CH2:18][CH2:19]1

Participants

5

Reactant 4

HCID 313Hydrochloric AcidHCID 702EthanolHCID 115623-BromoanilineHCID 17990004Ethyl 4-chloro-5,6,7,8-tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidine-7-carboxylate

Product 1

HCID 17990000Ethyl 4-[(3-bromophenyl)amino]-5,6,7,8-tetrahydro[1]benzothieno[2,3-d]pyrimidine-7-carboxylate

Sources & evidence

ORD record
ord-e0f1b98a092749bdb8d95200d639a05c
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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