Methanol → 5-Bromo-1'-methylspiro[indole-3,4'-piperidin]-2(1H)-one
Reaction equation
[CH3:1][N:2]1[CH2:3][CH2:4][C:5]2([C:6](=[O:14])[NH:7][c:8]3[cH:9][cH:10][cH:11][cH:12][c:13]32)[CH2:15][CH2:16]1.[CH3:25][C:26]#[N:27].[CH3:28][OH:29].[CH3:30][CH2:31][O:32][C:33](=[O:34])[CH3:35].[O:17]=[C:18]1[N:19]([Br:24])[C:20](=[O:21])[CH2:22][CH2:23]1>>[CH3:1][N:2]1[CH2:3][CH2:4][C:5]2([C:6](=[O:14])[NH:7][c:8]3[cH:9][cH:10][c:11]([Br:24])[cH:12][c:13]32)[CH2:15][CH2:16]1Participants
6
Sources & evidence
- ORD record
- ord-e42a2dee2d134877b59d0878b18693a4
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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