Ethanol → tert-Butyl 4-(5-nitro-1H-indol-3-yl)-5,6-dihydropyridine-1(2H)-carboxylate

HRID 681731Notes

Reaction equation

HRID 681731 reaction equation
[C:18](=[O:19])([O:20][C:21]([CH3:22])([CH3:23])[CH3:24])[N:25]1[CH2:26][CH2:27][C:28](=[O:31])[CH2:29][CH2:30]1.[CH2:13]1[CH2:14][NH:15][CH2:16][CH2:17]1.[CH3:32][CH2:33][OH:34].[N+:1](=[O:2])([O-:3])[c:4]1[cH:5][c:6]2[cH:7][cH:8][nH:9][c:10]2[cH:11][cH:12]1>>[N+:1](=[O:2])([O-:3])[c:4]1[cH:5][c:6]2[c:7]([C:28]3=[CH:27][CH2:26][N:25]([C:18](=[O:19])[O:20][C:21]([CH3:22])([CH3:23])[CH3:24])[CH2:30][CH2:29]3)[cH:8][nH:9][c:10]2[cH:11][cH:12]1

Participants

5

Reactant 4

HCID 702EthanolHCID 225235-NitroindoleHCID 31268PyrrolidineHCID 735900tert-Butyl 4-oxopiperidine-1-carboxylate

Product 1

HCID 54262828tert-Butyl 4-(5-nitro-1H-indol-3-yl)-5,6-dihydropyridine-1(2H)-carboxylate

Sources & evidence

ORD record
ord-f73f0ca1ed1b4450b7109172fe316a58
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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