Hydrochloric Acid → 4-(3-Fluoro-piperidin-4-yl)-morpholine

HRID 681889Notes

Reaction equation

HRID 681889 reaction equation
[C:2]([O:3][C:4](=[O:5])[N:9]1[CH2:10][CH:11]([F:21])[CH:12]([N:15]2[CH2:16][CH2:17][O:18][CH2:19][CH2:20]2)[CH2:13][CH2:14]1)([CH3:6])([CH3:7])[CH3:8].[CH3:22][CH2:23][O:24][CH2:25][CH3:26].[Cl:27][CH2:28][Cl:29].[ClH:1]>>[NH:9]1[CH2:10][CH:11]([F:21])[CH:12]([N:15]2[CH2:16][CH2:17][O:18][CH2:19][CH2:20]2)[CH2:13][CH2:14]1

Participants

5

Reactant 4

HCID 313Hydrochloric AcidHCID 3283Diethyl EtherHCID 6344DichloromethaneHCID 686713883-Fluoro-4-morpholin-4-yl-piperidine-1-carboxylic acid tert-butyl ester

Product 1

HCID 686707464-(3-Fluoro-piperidin-4-yl)-morpholine

Sources & evidence

ORD record
ord-f47713508c414afeb1cbbe8bfe7f3acf
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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