HuagongsheHuagongshe Chemistry Print Report · For research reference only
Thionyl Chloride → 3-tert-Butyldimethylsilyloxybenzoyl chloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | 3-{[tert-Butyl(dimethyl)silyl]oxy}benzoic acid | HCID 18369587 | — |
| Product | 3-tert-Butyldimethylsilyloxybenzoyl chloride | HCID 12448487 | — |
Reaction Steps
Into a 100 mL round bottom flask a mixture of 5 parts of 3-tert-butyldimethylsilyloxybenzoic acid and 25 mL of thionyl chloride was heated at reflux for 1 hr 30 min. The reaction mixture was concentrated under reduced pressure to yield 5.77 parts of an oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08822233B2 |
| Source dataset | uspto-grants-2014_09 |
| ORD ID | ord-13e1d7a64d23426bbff9517b16fca019 |
| Source note | uspto-grants-2014_09 |