Dimethylformamide → 2-(3-ethylsulfanyl-phenoxy)-5-fluoro-N-[cis-4-(2-methoxy-acetylamino)-cyclohexyl]-nicotinamide
Reaction equation
[C:34](=[O:35])([O-:36])[O-:37].[CH2:24]([CH3:25])[S:26][c:27]1[cH:28][c:29]([OH:33])[cH:30][cH:31][cH:32]1.[CH3:40][N:41]([CH3:42])[CH:43]=[O:44].[Cl:1][c:2]1[c:3]([C:4](=[O:5])[NH:6][CH:7]2[CH2:8][CH2:9][CH:10]([NH:13][C:14]([CH2:15][O:16][CH3:17])=[O:18])[CH2:11][CH2:12]2)[cH:19][c:20]([F:23])[cH:21][n:22]1.[Cs+:38].[Cs+:39]>>[c:2]1([O:33][c:29]2[cH:28][c:27]([S:26][CH2:24][CH3:25])[cH:32][cH:31][cH:30]2)[c:3]([C:4](=[O:5])[NH:6][CH:7]2[CH2:8][CH2:9][CH:10]([NH:13][C:14]([CH2:15][O:16][CH3:17])=[O:18])[CH2:11][CH2:12]2)[cH:19][c:20]([F:23])[cH:21][n:22]1Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-796041e76fdd4748aafc57a54a0fbe88
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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