Chloride → ethyl 6-chloro-5-amino-2-(trifluoromethyl)-2H-chromene-3-carboxylate

HRID 682555Notes

Reaction equation

HRID 682555 reaction equation
[CH3:26][OH:27].[Cl-:2].[Cl:3][c:4]1[c:5]([N:23]=[N+:24]=[N-:25])[c:6]2[c:11]([cH:12][cH:13]1)[O:10][CH:9]([C:14]([F:15])([F:16])[F:17])[C:8]([C:18](=[O:19])[O:20][CH2:21][CH3:22])=[CH:7]2.[OH2:1]>>[Cl:3][c:4]1[c:5]([NH2:23])[c:6]2[c:11]([cH:12][cH:13]1)[O:10][CH:9]([C:14]([F:15])([F:16])[F:17])[C:8]([C:18](=[O:19])[O:20][CH2:21][CH3:22])=[CH:7]2

Participants

5

Reactant 4

HCID 312ChlorideHCID 887MethanolHCID 962WaterHCID 58934903ethyl 6-chloro-5-azido-2-(trifluoromethyl)-2H-chromene-3-carboxylate

Product 1

HCID 58934551ethyl 6-chloro-5-amino-2-(trifluoromethyl)-2H-chromene-3-carboxylate

Sources & evidence

ORD record
ord-6e4c367e61fb44638855470e48bddb38
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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