Sodium ion → Tert-butyl 5-chlorospiro[indoline-3,3'-pyrrolidine]-1'-carboxylate

HRID 682775Notes

Reaction equation

HRID 682775 reaction equation
[BH4-:23].[CH2:25]1[O:26][CH2:27][CH2:28][CH2:29]1.[Cl:1][c:2]1[cH:3][c:4]2[c:8]([cH:9][cH:10]1)[NH:7][C:6](=[O:11])[C:5]21[CH2:12][N:13]([C:16](=[O:17])[O:18][C:19]([CH3:20])([CH3:21])[CH3:22])[CH2:14][CH2:15]1.[Na+:24]>>[Cl:1][c:2]1[cH:3][c:4]2[c:8]([cH:9][cH:10]1)[NH:7][CH2:6][C:5]21[CH2:12][N:13]([C:16](=[O:17])[O:18][C:19]([CH3:20])([CH3:21])[CH3:22])[CH2:14][CH2:15]1

Participants

5

Reactant 4

HCID 923Sodium ionHCID 8028TetrahydrofuranHCID 28123BorohydrideHCID 68762265Tert-butyl 5-chloro-2-oxospiro[indoline-3,3'-pyrrolidine]-1'-carboxylate

Product 1

HCID 69813251Tert-butyl 5-chlorospiro[indoline-3,3'-pyrrolidine]-1'-carboxylate

Sources & evidence

ORD record
ord-44e1ebf1e56747f7a1f878ca675f8828
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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