Methanol → N-(1-amino-3-cyclohexylpropan-2-yl)-5-chloro-4-(2-methylpyrazol-3-yl)thiophene-2-carboxamide
Reaction equation
[CH3:43][OH:44].[Cl:1][c:2]1[c:3](-[c:30]2[cH:31][cH:32][n:33][n:34]2[CH3:35])[cH:4][c:5]([C:7](=[O:8])[NH:9][CH:10]([CH2:11][CH:12]2[CH2:13][CH2:14][CH2:15][CH2:16][CH2:17]2)[CH2:18][N:19]2[C:20](=[O:21])[c:22]3[c:23]([cH:24][cH:25][cH:26][cH:27]3)[C:28]2=[O:29])[s:6]1.[NH2:36][NH2:37].[O:38]1[CH2:39][CH2:40][CH2:41][CH2:42]1>>[Cl:1][c:2]1[c:3](-[c:30]2[cH:31][cH:32][n:33][n:34]2[CH3:35])[cH:4][c:5]([C:7](=[O:8])[NH:9][CH:10]([CH2:11][CH:12]2[CH2:13][CH2:14][CH2:15][CH2:16][CH2:17]2)[CH2:18][NH2:19])[s:6]1Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-76a9645d05ee46179b248e6213742aef
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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