Dichloromethane → 4-[1-tert-Butoxycarbonyl-2-(3,4-dihydro-1H-isoquinoline-2-sulfonyl)-ethyl]-piperidine-1-carboxylic acid benzyl ester
Reaction equation
[CH2:18]([c:19]1[cH:20][cH:21][cH:22][cH:23][cH:24]1)[O:25][C:26](=[O:27])[N:28]1[CH2:29][CH2:30][CH:31]([CH:34]([CH2:35][S:36](=[O:37])(=[O:38])[Cl:39])[C:40](=[O:41])[O:42][C:43]([CH3:44])([CH3:45])[CH3:46])[CH2:32][CH2:33]1.[CH2:1]1[NH:2][CH2:3][CH2:4][c:5]2[cH:6][cH:7][cH:8][cH:9][c:10]21.[CH3:11][CH2:12][N:13]([CH2:14][CH3:15])[CH2:16][CH3:17].[Cl:47][CH2:48][Cl:49]>>[CH2:1]1[N:2]([S:36]([CH2:35][CH:34]([CH:31]2[CH2:30][CH2:29][N:28]([C:26]([O:25][CH2:18][c:19]3[cH:20][cH:21][cH:22][cH:23][cH:24]3)=[O:27])[CH2:33][CH2:32]2)[C:40](=[O:41])[O:42][C:43]([CH3:44])([CH3:45])[CH3:46])(=[O:37])=[O:38])[CH2:3][CH2:4][c:5]2[cH:6][cH:7][cH:8][cH:9][c:10]21Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-65d4d132a9e64754a9eb7ec2bec004c4
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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