Dichloromethane → [2-(4-fluoro-3-methoxyphenyl)-4-oxo-6-(3,6,6-trimethylperhydro-1,4-diazepin-1-yl)-4H-quinazolin-3-yl]acetic acid
Reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6]([CH2:7][n:8]1[c:9](-[c:29]2[cH:30][c:31]([O:36][CH3:37])[c:32]([F:35])[cH:33][cH:34]2)[n:10][c:11]2[cH:12][cH:13][c:14]([N:19]3[CH2:20][CH:21]([CH3:28])[NH:22][CH2:23][C:24]([CH3:26])([CH3:27])[CH2:25]3)[cH:15][c:16]2[c:17]1=[O:18])=[O:38].[Cl:46][CH2:47][Cl:48].[F:39][C:40]([F:41])([F:42])[C:43]([OH:44])=[O:45]>>[O:5]=[C:6]([CH2:7][n:8]1[c:9](-[c:29]2[cH:30][c:31]([O:36][CH3:37])[c:32]([F:35])[cH:33][cH:34]2)[n:10][c:11]2[cH:12][cH:13][c:14]([N:19]3[CH2:20][CH:21]([CH3:28])[NH:22][CH2:23][C:24]([CH3:26])([CH3:27])[CH2:25]3)[cH:15][c:16]2[c:17]1=[O:18])[OH:38]Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-6567b50a879b4a61aaf7d9bf124f8e3f
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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