Dichloromethane → Methyl 2-[(2-amino-3-phenylpropanoyl)amino]-1,3-thiazole-4-carboxylate

HRID 683232Notes

Reaction equation

HRID 683232 reaction equation
[CH3:1][O:2][C:3](=[O:4])[c:5]1[n:6][c:7]([NH:10][C:11]([CH:12]([CH2:13][c:14]2[cH:15][cH:16][cH:17][cH:18][cH:19]2)[NH:20][C:21]([O:22][C:23]([CH3:24])([CH3:25])[CH3:26])=[O:27])=[O:28])[s:8][cH:9]1.[Cl:36][CH2:37][Cl:38].[OH:29][C:30]([C:31]([F:32])([F:33])[F:34])=[O:35]>>[CH3:1][O:2][C:3](=[O:4])[c:5]1[n:6][c:7]([NH:10][C:11]([CH:12]([CH2:13][c:14]2[cH:15][cH:16][cH:17][cH:18][cH:19]2)[NH2:20])=[O:28])[s:8][cH:9]1

Participants

4

Reactant 3

HCID 6344DichloromethaneHCID 6422Trifluoroacetic acidHCID 87579771Methyl 2-[[2-[(2-methylpropan-2-yl)oxycarbonylamino]-3-phenylpropanoyl]amino]-1,3-thiazole-4-carboxylate

Product 1

HCID 87579455Methyl 2-[(2-amino-3-phenylpropanoyl)amino]-1,3-thiazole-4-carboxylate

Sources & evidence

ORD record
ord-992fc18b47354dbc96bee2296b689ff2
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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