Acetone → 2-chloro-N4-(4-n-butyloxyphenyl)-5-fluoro-4-pyrimidineamine
Reaction equation
[CH2:10]([CH2:11][CH2:12][CH3:13])[O:14][c:15]1[cH:16][cH:17][c:18]([NH2:19])[cH:20][cH:21]1.[CH3:25][C:26](=[O:27])[CH3:28].[Cl:1][c:2]1[n:3][cH:4][c:5]([F:9])[c:6]([Cl:8])[n:7]1.[ClH:22].[Na+:24].[OH-:23].[OH2:29]>>[Cl:1][c:2]1[n:3][cH:4][c:5]([F:9])[c:6]([NH:19][c:18]2[cH:17][cH:16][c:15]([O:14][CH2:10][CH2:11][CH2:12][CH3:13])[cH:21][cH:20]2)[n:7]1Participants
8
Sources & evidence
- ORD record
- ord-049b4768cc634506a53bb4ea240266a0
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
Loading…