Sodium ion → 7-[3-(4-acetylpiperazin-1-yl)propoxy]-N-[5-fluoro-7-(3-methoxyprop-1-yn-1-yl)-1,3-benzodioxol-4-yl]-6-methoxyquinazolin-4-amine
Reaction equation
[C:1]([CH3:2])(=[O:3])[N:4]1[CH2:5][CH2:6][N:7]([CH2:10][CH2:11][CH2:12][O:13][c:14]2[c:15]([O:25][CH3:26])[cH:16][c:17]3[c:18]([Cl:24])[n:19][cH:20][n:21][c:22]3[cH:23]2)[CH2:8][CH2:9]1.[CH3:43][Si:44]([N-:45][Si:46]([CH3:47])([CH3:48])[CH3:49])([CH3:50])[CH3:51].[F:27][c:28]1[c:29]([NH2:42])[c:30]2[c:31]([c:35]([C:37]#[C:38][CH2:39][O:40][CH3:41])[cH:36]1)[O:32][CH2:33][O:34]2.[Na+:52].[O:53]=[CH:54][N:55]([CH3:56])[CH3:57]>>[C:1]([CH3:2])(=[O:3])[N:4]1[CH2:5][CH2:6][N:7]([CH2:10][CH2:11][CH2:12][O:13][c:14]2[c:15]([O:25][CH3:26])[cH:16][c:17]3[c:18]([NH:42][c:29]4[c:28]([F:27])[cH:36][c:35]([C:37]#[C:38][CH2:39][O:40][CH3:41])[c:31]5[c:30]4[O:34][CH2:33][O:32]5)[n:19][cH:20][n:21][c:22]3[cH:23]2)[CH2:8][CH2:9]1Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-f7e48e6c498c4d01967abfbd1d074193
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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