Hydrochloric Acid → 4-(2-(5-fluoro-1H-indol-4-yl)-6-(piperidin-4-ylmethyl)pyrido[3,2-d]pyrimidin-4-yl)morpholine

HRID 683526Notes

Reaction equation

HRID 683526 reaction equation
[ClH:41].[F:1][c:2]1[c:3](-[c:11]2[n:12][c:13]([N:35]3[CH2:36][CH2:37][O:38][CH2:39][CH2:40]3)[c:14]3[c:15]([n:16]2)[cH:17][cH:18][c:19]([CH2:21][CH:22]2[CH2:23][CH2:24][N:25]([C:28]([O:29][C:30]([CH3:31])([CH3:32])[CH3:33])=[O:34])[CH2:26][CH2:27]2)[n:20]3)[c:4]2[cH:5][cH:6][nH:7][c:8]2[cH:9][cH:10]1.[O:42]1[CH2:43][CH2:44][O:45][CH2:46][CH2:47]1>>[F:1][c:2]1[c:3](-[c:11]2[n:12][c:13]([N:35]3[CH2:36][CH2:37][O:38][CH2:39][CH2:40]3)[c:14]3[c:15]([n:16]2)[cH:17][cH:18][c:19]([CH2:21][CH:22]2[CH2:23][CH2:24][NH:25][CH2:26][CH2:27]2)[n:20]3)[c:4]2[cH:5][cH:6][nH:7][c:8]2[cH:9][cH:10]1

Participants

4

Reactant 3

HCID 313Hydrochloric AcidHCID 312751,4-DioxaneHCID 53378677tert-butyl 4-((2-(5-fluoro-1H-indol-4-yl)-4-morpholinopyrido[3,2-d]pyrimidin-6-yl)methyl)piperidine-1-carboxylate

Product 1

HCID 584049944-(2-(5-fluoro-1H-indol-4-yl)-6-(piperidin-4-ylmethyl)pyrido[3,2-d]pyrimidin-4-yl)morpholine

Sources & evidence

ORD record
ord-8ca7adafd3de43cfad6334ea0e0cc228
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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