Bicarbonate Ion → Ethyl 3-(benzyl(3-ethoxy-3-oxopropyl)amino)-2,2-difluoropropanoate
Reaction equation
[Br:1][C:2]([C:3](=[O:4])[O:5][CH2:6][CH3:7])([F:8])[F:9].[CH2:10]([CH3:11])[O:12][C:13]([CH2:14][CH2:15][N:16]([CH2:17][c:18]1[cH:19][cH:20][cH:21][cH:22][cH:23]1)[CH2:24][n:25]1[c:26]2[cH:27][cH:28][cH:29][cH:30][c:31]2[n:32][n:33]1)=[O:34].[CH2:40]1[O:41][CH2:42][CH2:43][CH2:44]1.[Na+:39].[O-:35][C:36]([OH:37])=[O:38].[Zn:45]>>[C:2]([C:3](=[O:4])[O:5][CH2:6][CH3:7])([F:8])([F:9])[CH2:24][N:16]([CH2:15][CH2:14][C:13]([O:12][CH2:10][CH3:11])=[O:34])[CH2:17][c:18]1[cH:19][cH:20][cH:21][cH:22][cH:23]1Participants
7
Sources & evidence
- ORD record
- ord-a104802d11f44474aa7c055e07211c9c
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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