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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 683723Generated: October 31, 2026

Citric Acid → 6-[3-(3,4-Difluoro-phenyl)-5-hydroxymethyl-isoxazol-4-ylmethoxy]-nicotinic acid methyl ester

https://huagongshe.com/reaction/683723

Reaction equation

Participants

RoleNameHCIDCharge
ReactantCitric AcidHCID 311—
ReactantMethanolHCID 887—
ReactantSodium ionHCID 923—
ReactantEthyl AcetateHCID 8857—
ReactantBorohydrideHCID 28123—
Reactant6-[3-(3,4-Difluoro-phenyl)-5-formyl-isoxazol-4-ylmethoxy]-nicotinic acid methyl esterHCID 86646256—
Product6-[3-(3,4-Difluoro-phenyl)-5-hydroxymethyl-isoxazol-4-ylmethoxy]-nicotinic acid methyl esterHCID 66718164—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (3/10)
ORD IDord-136a5dad657b441bbd3905574cee7170
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (3/10)