Citric Acid → 6-[3-(3,4-Difluoro-phenyl)-5-hydroxymethyl-isoxazol-4-ylmethoxy]-nicotinic acid methyl ester
Reaction equation
[BH4-:28].[CH3:1][O:2][C:3]([c:4]1[cH:5][n:6][c:7]([O:10][CH2:11][c:12]2[c:13](-[c:19]3[cH:20][c:21]([F:26])[c:22]([F:25])[cH:23][cH:24]3)[n:14][o:15][c:16]2[CH:17]=[O:18])[cH:8][cH:9]1)=[O:27].[CH3:43][CH2:44][O:45][C:46](=[O:47])[CH3:48].[CH3:49][OH:50].[Na+:29].[OH:30][C:31]([CH2:32][C:33]([C:34](=[O:35])[OH:36])([CH2:37][C:38](=[O:39])[OH:40])[OH:41])=[O:42]>>[CH3:1][O:2][C:3]([c:4]1[cH:5][n:6][c:7]([O:10][CH2:11][c:12]2[c:13](-[c:19]3[cH:20][c:21]([F:26])[c:22]([F:25])[cH:23][cH:24]3)[n:14][o:15][c:16]2[CH2:17][OH:18])[cH:8][cH:9]1)=[O:27]Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-136a5dad657b441bbd3905574cee7170
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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