Dichloromethane → N-{3-Chloro-4-[2-(2-chloro-pyridin-4-yl)-3,3,3-trifluoro-2-hydroxy-1-methyl-propyl]-phenyl}-benzamide

HRID 683855Notes

Reaction equation

HRID 683855 reaction equation
[C:10]([c:11]1[cH:12][cH:13][cH:14][cH:15][cH:16]1)(=[O:17])[Cl:18].[CH:1]([N:2]([CH2:3][CH3:4])[CH:5]([CH3:6])[CH3:7])([CH3:8])[CH3:9].[Cl:42][CH2:43][Cl:44].[NH2:19][c:20]1[cH:21][c:22]([Cl:41])[c:23]([CH:26]([C:27]([C:28]([F:29])([F:30])[F:31])([OH:32])[c:33]2[cH:34][c:35]([Cl:39])[n:36][cH:37][cH:38]2)[CH3:40])[cH:24][cH:25]1>>[C:10]([c:11]1[cH:12][cH:13][cH:14][cH:15][cH:16]1)(=[O:17])[NH:19][c:20]1[cH:21][c:22]([Cl:41])[c:23]([CH:26]([C:27]([C:28]([F:29])([F:30])[F:31])([OH:32])[c:33]2[cH:34][c:35]([Cl:39])[n:36][cH:37][cH:38]2)[CH3:40])[cH:24][cH:25]1

Participants

5

Reactant 4

HCID 6344DichloromethaneHCID 7412Benzoyl chlorideHCID 81531DiisopropylethylamineHCID 866291093-(4-Amino-2-chloro-phenyl)-2-(2-chloro-pyridin-4-yl)-1,1,1-trifluoro-butan-2-ol

Product 1

HCID 25254771N-{3-Chloro-4-[2-(2-chloro-pyridin-4-yl)-3,3,3-trifluoro-2-hydroxy-1-methyl-propyl]-phenyl}-benzamide

Sources & evidence

ORD record
ord-1f0144a2702043bd9efff7f485145564
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

Loading…