Tetrahydrofuran → 2-[5-(3-Chlorophenyl)-6-(4-chlorophenyl)-1-(1-hydroxybutan-2-yl)-3-methyl-2-oxopiperidin-3-yl]acetic acid
Reaction equation
[C:1]([Si:2]([c:3]1[cH:4][cH:5][cH:37][cH:38][cH:39]1)([O:6][CH2:7][CH:8]([CH2:9][CH3:10])[N:11]1[C:12](=[O:36])[C:13]([CH3:31])([CH2:32][C:33](=[O:34])[OH:35])[CH2:14][CH:15]([c:24]2[cH:25][c:26]([Cl:30])[cH:27][cH:28][cH:29]2)[CH:16]1[c:17]1[cH:18][cH:19][c:20]([Cl:23])[cH:21][cH:22]1)[c:40]1[cH:41][cH:42][cH:43][cH:44][cH:45]1)([CH3:46])([CH3:47])[CH3:48].[CH2:50]([N+:51]([CH2:52][CH2:53][CH2:54][CH3:55])([CH2:56][CH2:57][CH2:58][CH3:59])[CH2:60][CH2:61][CH2:62][CH3:63])[CH2:64][CH2:65][CH3:66].[CH2:67]1[O:68][CH2:69][CH2:70][CH2:71]1.[F-:49]>>[OH:6][CH2:7][CH:8]([CH2:9][CH3:10])[N:11]1[C:12](=[O:36])[C:13]([CH3:31])([CH2:32][C:33](=[O:34])[OH:35])[CH2:14][CH:15]([c:24]2[cH:25][c:26]([Cl:30])[cH:27][cH:28][cH:29]2)[CH:16]1[c:17]1[cH:18][cH:19][c:20]([Cl:23])[cH:21][cH:22]1Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-f741eb3aa916404090a72b556cee3aa2
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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